Maryland Medicaid is implementing a significant change to its provider enrollment system. The longstanding Electronic Provider Revalidation and Enrollment Portal (ePREP) is being replaced by the Maryland Provider Registration and Information Management Enterprise (MPRIME).

The new system is scheduled to launch on October 13, 2026, affecting healthcare providers who enroll, revalidate, or maintain enrollment information with Maryland Medicaid.

For existing Medicaid providers and organizations preparing to participate in the program, understanding this transition is important to avoiding enrollment delays, account-access issues, and potential disruptions to Medicaid participation.

What Is MPRIME?

MPRIME is Maryland Medicaid's new online provider enrollment and information management system.

It will replace ePREP as the primary portal for:

Initial Maryland Medicaid provider enrollment
Medicaid enrollment revalidation
Updating provider demographic and organizational information
Reporting ownership and other enrollment changes
Managing provider account information and authorized users
Reviewing enrollment-related correspondence

Although MPRIME introduces a new platform and account-management process, it does not replace the underlying state licensing requirements applicable to healthcare organizations.

MPRIME vs. ePREP: What Is Changing?

ePREP — Previous System	MPRIME — New System
Previously used for Maryland Medicaid enrollment	Replaces ePREP for enrollment
Managed Medicaid revalidation applications	Manages revalidation applications
Accepted provider demographic and ownership updates	Supports enrollment changes and account updates
Maintained individual user accounts and provider associations	Requires new user registration and association with provider accounts
Stored enrollment documents and correspondence	Existing provider enrollment records transfer, but historical ePREP document attachments do not

One of the most important distinctions concerns account access.

Maryland Medicaid has confirmed that existing provider enrollment accounts will transfer to MPRIME. However, individual users must establish their MPRIME access and associate themselves with the provider accounts they are authorized to manage.

Existing group and rendering-provider affiliations will be retained, but user access is not automatically transferred in the same manner.

Important MPRIME Transition Dates

Maryland implemented a phased transition during 2026.

July 1, 2026 — Application hold for moderate- and high-risk providers

Maryland Medicaid began its application hold for moderate- and high-risk provider types. New or updated applications submitted during this period are returned without processing; they are not retained in a processing queue.

August 1, 2026 — Application hold expanded

The application hold expanded to limited-risk provider types, with new or updated applications likewise returned without processing.

September 30, 2026 — Final ePREP document-access deadline

Providers were instructed to download historical ePREP documents by 5:00 p.m. on September 30.

October 1, 2026 — ePREP access ended

Maryland discontinued provider access to ePREP. Historical documents left in the system are no longer accessible through the previous portal.

October 13, 2026 — Scheduled MPRIME launch

Maryland Medicaid has announced October 13 as the scheduled launch date for the replacement system.

Providers are not required to create their MPRIME accounts on the first day. Account registration and provider association may be completed on or after the launch date.

Will Existing Medicaid Providers Need to Enroll Again?

Not simply because the system is changing.

The system transition itself does not require existing providers to submit a new enrollment application. Transferred records do not, however, resolve outstanding revalidation, suspension, or enrollment issues. Providers should review those matters separately and retain their own copies of approvals, correspondence, and supporting records.

What About Medicaid Revalidation?

Maryland Medicaid requires providers to periodically revalidate their enrollment to remain active and in good standing.

In preparation for the transition, Maryland issued early revalidation notices to certain providers whose revalidation dates fell between May and October 2026.

Affected providers were instructed to complete revalidation within the specified 90-day response period.

Providers who failed to complete required revalidation actions may be subject to suspension.

Once MPRIME is operational, revalidation will be managed through the new system.

Providers should carefully review their current enrollment status, outstanding notices, and any required corrective actions.

Check SDAT Good Standing Before Applying

Maryland Medicaid's July 2026 enrollment FAQ confirms that MPRIME will interface with Maryland Business Express to verify business registration information.

Providers must maintain an appropriate State Department of Assessments and Taxation (SDAT) identification number in good standing.

An applicant whose SDAT registration is not in good standing will be unable to continue or submit the enrollment application until the issue is resolved.

Maryland also requires organizational enrollment information to match applicable legal business records.

Providers preparing to enroll should confirm their SDAT standing and review the consistency of their legal business name, IRS documentation, and enrollment information.

What Happens to Applications Delayed by the Transition?

Maryland Medicaid established temporary application holds while preparing to replace ePREP.

The Department also announced a limited backdating policy for certain newly enrolling providers affected by those holds.

Under Provider Transmittal PT 94-26, newly enrolling providers who submit a complete, correct, and processable MPRIME application by December 31, 2026, may qualify for a backdated enrollment effective date.

The potential effective date is based on the later of the applicable application-hold start date or the provider's license issuance date.

However, backdating is not guaranteed.

Providers cannot bill or receive payment for Medicaid claims before enrollment approval, and organizations delivering services before approval assume financial risk.

Agencies should not interpret potential retroactive enrollment as authorization to provide or bill for services without satisfying other applicable program requirements.

Does MPRIME Replace Maryland Healthcare Licensing?

No. MPRIME addresses Medicaid provider enrollment, not the state's separate healthcare licensing process.

For example, Maryland Residential Service Agencies (RSAs) continue to obtain their state licenses through the Maryland Department of Health's Office of Health Care Quality (OHCQ).

RSA licensure is governed by COMAR 10.07.05 and remains separate from Maryland Medicaid enrollment.

A private-pay RSA does not need to enroll through MPRIME solely to obtain an OHCQ license.

However, an RSA that intends to participate in Maryland Medicaid must satisfy the applicable Medicaid provider-enrollment and program participation requirements in addition to maintaining any required state license.

The same general distinction applies to other licensed healthcare organizations, including home health agencies and hospices: state licensure and Medicaid enrollment are separate regulatory processes, even when both are necessary for the organization's intended operations.

How Should Providers Prepare for MPRIME?

Organizations preparing to use the new system should:

Verify enrollment status. Confirm that existing provider records are active and identify outstanding revalidation or enrollment issues.
Confirm SDAT good standing. Resolve business registration problems before submitting applications.
Identify authorized account users. Determine which administrators, employees, or authorized representatives need access.
Organize enrollment records. Maintain copies of licenses, IRS documents, W-9 forms, provider identifiers, enrollment approvals, and other supporting information.
Establish MPRIME user accounts. Beginning on or after the scheduled launch, create user access and associate the appropriate provider records.
Review official training resources. Maryland has published instructions and training materials covering account registration, provider enrollment, updates, and revalidation.

The state's enrollment FAQ indicates that first-time MPRIME user registration requires a mobile number capable of receiving text messages.

Providers managing multiple accounts should also review the system's administrator and read-only access permissions.

Where Can Providers Find Official MPRIME Guidance?

The Maryland Department of Health has established a dedicated MPRIME information page and training center.

Providers should rely on these official resources for the latest implementation instructions and system updates.

Official Maryland Medicaid resources:

Maryland Medicaid has also identified mdh.mprimegolive@maryland.gov for questions regarding the transition.

Enrollment Support and Next Steps

The transition changes how providers manage Medicaid enrollment, while state licensure remains a separate process. Confirm your enrollment status, prepare authorized user access, and use Maryland's official resources for current instructions.

For organizations seeking provider-enrollment assistance, our partner ClearPath Credentialing provides enrollment support. NorthEnd's role focuses on licensing; SouthStart develops policy and compliance materials.

Explore the Maryland State Licensing Guide for an overview of the agency licensing paths.

This article is provided for general informational purposes and reflects Maryland Medicaid guidance reviewed October 9, 2026. Implementation dates and administrative procedures may change. Providers should consult the Maryland Department of Health for current instructions.

Informational guidance reviewed October 9, 2026. Check Maryland Medicaid for current system instructions, deadlines, and provider-specific requirements.